About Us

The Institute has a growing staff of epidemiologists, statisticians, and exposure scientists and collaborates with the Department of Clinical Epidemiology, Aarhus University, Aarhus, Denmark and the University of Michigan, Ann Arbor, Michigan.

Our services include:

  • Assist clients in evaluating their need for epidemiological support
  • Provide consulting services to critically evaluate scientific issues and approaches to problem solving
  • Study design and conduct
  • Data management and statistical analysis
  • Manuscript writing and publication
  • Preparing review articles and meta-analyses compliant with the International Committee of Medical Journal Editors (ICMJE) standards
  • Prepare epidemiology sections for orphan drug applications and other regulatory documents

Jon P. Fryzek – Co-Founder, CEO Dr. Fryzek, PhD, has 20 years of experience in the pharmaceutical industry and private consulting firms. He has conducted epidemiologic studies of cancer, connective tissue diseases, neurological diseases, infectious diseases, chronic renal failure, and medical devices. He has led numerous occupational studies, including studies of aerospace workers, automotive workers, diaper manufacturers, welders, motion picture film processing workers, and chemical manufacturers. His environmental studies involved examining the risk associated with DDT and other pesticides for pancreatic cancer patients, as well as the risk of environmental chromium associated with cancer. In support of Drug Development and Drug Safety, he has performed studies elucidating the natural history of various diseases, including descriptive incidence studies, “real-world” disease treatment pattern studies, and co-morbidity assessments. Dr. Fryzek has over 150 peer-reviewed manuscripts, book chapters, and scientific meeting abstracts. He has published in the New England Journal of Medicine, the Annals of Internal Medicine, the Journal of the National Cancer Institute, and the Journal of Occupational and Environment Medicine, among others, and is a scientific reviewer for a number of journals, including the American Journal of Epidemiology, Cancer Epidemiology, Biomarkers and Prevention, and the International Journal of Cancer. Dr. Fryzek is currently Adjunct Professor, University of Pittsburgh School of Public Health and Visiting Professor in the Department of Clinical Epidemiology, Aarhus University, Aarhus, Denmark. Email Jon Fryzek direct: +1.240.688.1326 Dr. Fryzek’s CV August 2018

David H. Garabrant – Co-Founder, President Dr. Garabrant, MD, MPH has over 30 years of experience in the design and conduct of epidemiological studies, litigation support, and independent research. He is board certified in Internal Medicine, Preventive Medicine, and Occupational Medicine. His research has focused on the long-term health effects of chemicals and pharmaceutical agents and devices. Specific topics include studies of exposure pathways for environmental dioxin contamination, meta-analyses of occupational risks related to motor vehicle mechanics and brake mechanics, cohort mortality studies, and case-control studies of pancreas, colorectal cancer, and head and neck cancer. Dr. Garabrant has over 350 research articles, book chapters, and abstracts related to these areas. He has published in many scientific journals including Occupational and Environmental Medicine, the Journal of the National Cancer Institute, Cancer Research and the Journal of Neurotoxicology. In addition, he was appointed to membership on the Safety and Occupational Health Study Section of the National Institutes of Health (NIH) in 1992 and served on that Study Section until 1996, having been appointed by Secretary of HHS Donna Shalala as Chair for the 1995-96 year. In 2007, he was awarded the Research Excellence Award from the University of Michigan Risk Center for his work on the health effects of dioxins. He is Emeritus Professor of Occupational Medicine and Epidemiology at the University of Michigan. Email David Garabrant direct: +1.734.646.2692

Dominik D. Alexander – Principal Epidemiologist Dr. Alexander, PhD, MSPH, has extensive experience in health research methodology, meta-analysis, and disease causation, particularly in the conceptualization, design, analysis, and interpretation of epidemiologic studies. He has published on a diverse range of topics and types of studies, including original epidemiologic research, qualitative reviews, systematic weight-of-evidence assessments, and quantitative meta-analyses. Because of his expertise in research methodology, Dr. Alexander has served as principal investigator on numerous projects involving a wide variety of exposures and health outcomes. His research areas include: occupational and environmental exposures, such as asbestos, benzene, trichloroethylene, solvents, pesticides, arsenic, and dioxin; community health studies and cluster investigations involving air, water, and soil exposures; clinical, pharmacoepidemiology, and medical device studies including clinical trial design and support. In addition, Dr. Alexander has extensive experience in nutritional epidemiology and has conducted systematic reviews and meta-analyses of dietary and nutritional factors and cancer, cardiovascular disease, type 2 diabetes, hypertension, and body composition. His work in this area has involved studies of dietary patterns, intake of whole foods, and dietary supplements, such as meat and fat intake, dairy and egg consumption, breakfast eating, multivitamin and mineral supplements, fish oil, caffeine, and infant formula. Dr. Alexander has over 180 peer-reviewed manuscripts, professional presentations, abstracts, and book chapters. He frequently presents on the understanding and interpretation of epidemiologic evidence in a variety of professional venues, such as national conventions, scientific conferences, and governmental regulatory forums. Dr. Alexander serves on the editorial board of the American Journal of Clinical Nutrition. In addition, he regularly serves on scientific committees and scientific advisory meetings. Dr. Alexander was awarded a National Cancer Institute Fellowship for Cancer Prevention and Control and was the 2010 recipient of the UAB School of Public Health alumnus award for scientific excellence, based on recognition of his “significant scientific contributions through demonstrated commitment and exemplary leadership in empirical research, research methodology, or theory building or adaptation.” Dr. Alexander is a Visiting Professor of Epidemiology at the University of Copenhagen in Copenhagen, Denmark. Email Dominik Alexander direct: +1.630.390.8190 Dr. Alexander’s CV August 2018

Sarah S. Cohen –Principal Epidemiologist Dr. Cohen, PhD, MS, received her PhD in Cancer Epidemiology from the University of North Carolina at Chapel Hill and has 15 years of experience in the design and conduct of epidemiological studies. Her expertise includes the areas of cancer, obesity, occupational health, radiation health effects, and pharmacoepidemiology. Dr. Cohen has published numerous papers examining behavioral and genetic determinants of cancer and metabolic-related conditions such as obesity and diabetes, racial disparities in cancer, biomarkers of cancer and obesity, and cancer screening patterns. As a result of her expertise in the area of obesity epidemiology, she was inducted as a Fellow of The Obesity Society in 2012. She has also collaborated on multiple studies of worker health among radiation-exposed workers as well as occupational cohort studies of aerospace workers, welders, motion picture film processing workers, and chemical manufacturers. In addition to her epidemiology training, Dr. Cohen received a BS and MS in biostatistics and brings a strong set of analytic skills to the EpidStat team. Dr. Cohen’s publications have appeared in journals such as the Journal of the National Cancer Institute, American Journal of Epidemiology, Cancer, Obesity, and the Journal of Occupational and Environment Medicine. She serves as a scientific reviewer for many journals including American Journal of Epidemiology; Cancer Epidemiology, Biomarkers, and Prevention; Clinical Endocrinology; Obesity; PLoS One; and Preventive Medicine. Dr. Cohen is currently Adjunct Assistant Research Professor of Medicine in the Division of Epidemiology within the Department of Medicine at the Vanderbilt University School of Medicine. Dr. Cohen’s CV August 2018

Bob Nordyke – Principal Economist Dr. Nordyke, PhD, MS, brings over 25 years of project and organizational leadership, health economics, outcomes research, and health policy experience to this project. Over the last 15 years, Bob has focused on the global pharmaceutical industry, gaining roles of increasing impact in health economics consulting and in pharmaceutical industry. In addition to his role at EpidStat, Bob is currently an adjunct professor at the UCLA Fielding School of Public Health in the Dept. of Health Policy and Management and is also a senior researcher at the UCLA Center for Health Policy Research. Before establishing the health economics practices at ICON/PriceSpective and more recently at Precision for Medicine, Bob was part of Amgen’s Global Health Economics team. At Amgen he served as the therapeutic area head for inflammation, the global payer lead and global health economics lead in oncology supportive care, and was the program lead for an EMR-based registry capability for Amgen’s entire oncology portfolio. Prior to Amgen, Bob was the director of outcomes research at Cerner LifeSciences and a research fellow at the RAND Corporation. Bob received his BS in engineering from Rose-Hulman Institute of Technology, an MS in engineering from the University of Texas-Austin, and a PhD in Public Policy Analysis (Health Policy) from the RAND Graduate School. Email Bob Nordyke direct: +1.310.210.1582 Dr. Nordyke’s CV October 2016

Claire Roy – Research Assistant Ms. Roy recently graduated from the University of Nebraska-Lincoln where she obtained her BS in Psychology with a minor in Biology. Currently she is working toward her MPH at George Washington University. Her research interests include Health Advocacy and Health Promotion with a special focus on research within the Veteran population and advocating for Veteran healthcare needs. Email Claire Roy

Cynthia Gutierrez – Epidemiologist Ms. Gutierrez, MPH, holds a Master’s degree in Global Health Epidemiology from the University of Michigan School of Public Health, and a Bachelor’s degree in Biology with an emphasis in cellular and molecular biology from California State University, Channel Islands. During her time at the University of Michigan, her research included longitudinal analysis of the effects of market integration on nutritional status of adults. Ms. Gutierrez previously held an internship through the University of Michigan in rural Ecuador, summarizing and presenting the results of a ten-year longitudinal study to the participating communities. Her research interests include vector-borne diseases, health communication in middle- and low-income settings, and nutritional epidemiology. Email Cynthia Gutierrez

Gina Nicholson – Health Economist Ms. Nicholson builds evidence to answer strategic research questions in multiple therapy areas. Her deep research experience centers around outcomes research design and analysis. Within health economics and market access, Gina focuses on developing product value strategy, having developed HEOR evidence generation strategies, value stories/dossiers, and evidence synthesis. Email Gina Nicholson

Heidi Reichert – Biostatistician Ms. Reichert, MA, earned her graduate degree at the University of Michigan. She has 10 years of experience as a statistical consultant and analyst for a diverse set of projects involving medical record data, claims data, survey data, and data from the University of Michigan Dioxin Exposure Study. Her methodological interests include risk adjustment methods and models for clustered and longitudinal data. She has extensive data management and programming experience in Stata and also uses SAS and R. Ms. Reichert has given client workshops on data analysis planning and data management, and lectured on statistical methods at the University of Michigan School of Public Health. She has presented her work at methods conferences including the American Statistical Association’s International Conference for Health Policy Statistics and the Conference on Statistical Practice. Co-authored manuscripts by Ms. Reichert appear in Annals of Internal Medicine, Infection Control and Hospital Epidemiology, Journal of the American Geriatrics Society, Journal of General Internal Medicine, Blood Advances and Journal of Vascular and Endovascular Surgery. Email Heidi Reichert

Jenna Coalson – Epidemiologist Dr. Coalson, PhD, MPH, brings specialized knowledge on infectious diseases. Ms. Coalson recently completed her PhD in Epidemiologic Sciences at the University of Michigan School of Public Health, where she researched infectious disease transmission dynamics.  Her dissertation research focused on defining the role that asymptomatic cases play in the transmission of malaria parasites. She previously obtained an MPH in International Health Epidemiology from the University of Michigan and a BA in Human Biology, concentrating on The Biological and Social Aspects of Infectious Disease, from Stanford University.  She has experience in both laboratory and field epidemiologic research, having had internships in the San Mateo County Department of Public Health and the Kintampo Health Research Centre in Ghana and having worked briefly in the laboratories of the Stanford University Microbiology and Immunology Department, the University of Nebraska Medical Center Department of Cellular and Integrative Physiology, and the Malawi College of Medicine.  Prior to beginning work with EpidStat, she worked for two years as a Scientist in the Exposure Assessment and Dose Reconstruction group at Exponent, Inc., where she assisted with a large occupational cohort study and performed various literature reviews on issues relating to asbestos exposure from consumer products, incidence and prevalence of various osseous and blood-related diseases and cancers, and treatment patterns in metastatic breast cancer. Email Jenna Coalson

Jessica Yaser – Research Assistant Ms. Yaser is working toward a Master’s degree in Occupational & Environmental Epidemiology at the University of Michigan School of Public Health, expected May 2019. She holds a Bachelor’s degree in Public Health from Purdue University with concentrations in Behavioral Social Sciences and Environmental Health. Ms. Yaser previously worked for the Vanderburgh County Health Department in Evansville, Indiana, where she helped design a health promotion program to reduce fetal and infant mortality. Her research interests include nutritional epidemiology, the built environment, and occupational exposures. Email Jessica Yaser

Julie Hahn – Epidemiologist Ms. Hahn, MPH, holds a Master’s degree in General Epidemiology from the University of Michigan School of Public Health, and Bachelor’s degree in Radiologic Science from the University of North Carolina Chapel Hill. During her time at the University of Michigan, her research included evaluating associations between diagnosed and undiagnosed diabetes and different dimensions of depression among Asian Americans using NHANES data. Ms. Hahn previously held an internship at the University of Michigan where she worked on a project revisiting the Tecumseh Community Health Study retrieving historical study documents and investigating survey methods to recreate a characterization of the Tecumseh community and the participants of the study. She has experience in literature review, statistical methods, and conducting statistical analysis using SAS. Her research interests include chronic diseases and nutritional epidemiology. Email Julie Hahn

Lauren Bylsma – Epidemiologist Ms. Bylsma earned her MPH at the University of Michigan School of Public Health in the Epidemiology and International Health program. While in school, she worked as a research assistant on a prospective cohort study evaluating the effects of air pollution on pre-term birth in Mexico City and interned at the Universidad Nacional Autónoma de México in Mexico City managing nutritional data and analyzing fetal growth effects of maternal dietary patterns. In her 5 years at EpidStat, Ms. Bylsma has worked in the areas of cancer epidemiology, nutritional epidemiology, pharmacoepidemiology, and the epidemiology of rare diseases. She has conducted several large systematic literature reviews and meta-analyses across multiple therapeutic areas. Ms. Bylsma has also taught an integrative capstone seminar in the Department of Public Health at Calvin College and has presented work at conferences across research settings, including American Society of Hematology, European Society for Medical Oncology, Experimental Biology, and International Society for Pharmacoeconomics and Outcomes Research. She has co-authored numerous manuscripts in journals such as Nutrition Journal, European Journal of Vascular and Endovascular Surgery, Cancer, Blood Advances, and the American Journal of Clinical Nutrition. Email Lauren Bylsma

Luke Shenton – Epidemiologist Mr. Shenton, MPH, earned a Master’s degree in Epidemiology from the University of Michigan School of Public Health and a Bachelor of Science degree in Neuroscience from the University of Michigan. His research interests include maternal and child health, social, and, infectious disease epidemiology. During his time at the University of Michigan, Mr. Shenton conducted analyses on large nationally representative data sets to evaluate vaccination program performance in low and middle income countries. He has authored publications in journals such as Maternal and Child Health Journal and Vaccine. Mr. Shenton has experience in literature review, data collection, statistical methods, and programming in SAS and R. Email Luke Shenton

Lynn Zwica – Senior Research Associate (Exposure Scientist) Ms. Zwica, MS, has over 15 years of experience working in academic research and private consulting, including extensive experience in the area of litigation support. Ms. Zwica is a trained exposure scientist, having obtained MS degrees in both Environmental Health and Industrial Hygiene at the University of Michigan School of Public Health as part of the Hazardous Substances Academic Training Program. She also holds a BS in Chemical Engineering from the University of Michigan. Ms. Zwica’s scientific interests include occupational and environmental exposure assessment, risk assessment, and cancer etiology, with a focus on lymphohematopoietic disease and its relationship to solvent exposure. As an academic researcher she played a significant role in the design and conduct of numerous projects most notably as the household dust sampling coordinator for the University of Michigan Dioxin Exposure Study where she oversaw and participated in the development of the sampling protocol as well as supervised the sampling and handling of over 700 household dust samples. In the private sector, Ms. Zwica has been involved in industry research projects as well as provided litigation support to numerous clients, primarily focusing on exposure to chemicals and cancer. Email Lynn Zwica

Neha Mandava – Epidemiologist Ms. Mandava, MPH, holds a Master’s degree in General Epidemiology at the University of Michigan School of Public Health and Bachelor’s degrees in Biology and Politics from Willamette University. Her research at the University of Michigan included literature reviews for chronic illnesses, such as Type II Diabetes and Hypertension. Ms. Mandava previously held an internship at the Karmanos Cancer Institute where she collaborated on a study examining depression in cancer patients and the brain-derived neurotrophic factor gene. She has experience conducting statistical analysis using SAS and R and her research interests include chronic illnesses, cancer, and genetics. Email Neha Mandava

Naimisha Movva – Epidemiologist Ms. Movva, MPH, holds a Master’s degree in Chronic Disease Epidemiology from the Yale School of Public Health and Bachelor’s degrees in Biological Sciences and Psychology from the University of Delaware. Her research interests include maternal and child health, nutritional, and perinatal epidemiology. During her time at Yale University, Ms. Movva evaluated how the Supplementary Program for Women, Infants, and Children (WIC) used evidence to drive programmatic decision making to encourage more evidence-based breastfeeding policies. She previously held an internship at the University of Oxford through the Value Based Healthcare Programme where she evaluated the effectiveness of the Quality Outcomes Framework, a pay-for-performance initiative in England. Ms. Movva also has experience conducting statistical analyses and teaching statistical programming. Email Naimisha Movva

Stacey Rosenzweig – Epidemiologist Ms. Rosenzweig, MPH, earned her Master’s degree in Epidemiology from the University of Michigan School of Public Health and BA in Biology from Whitman College. During her time at Michigan, Ms. Rosenzweig conducted analyses on partial-term births, menopausal hormone therapy and ovarian cancer survival using data from the Ovarian Cancer Association Consortium. She also spent a summer in Dar es Salaam, Tanzania collecting long term survival data from a Burkitt’s lymphoma clinical trial and evaluated the factors affecting survival for children enrolled in the trial. Prior to receiving her MPH, Ms. Rosenzweig worked at a small biotech company in Berkeley, CA helping to manage immuno-oncology clinical trials in mesothelioma, ovarian, and pancreatic cancer. Ms. Rosenzweig has experience in literature review, data collection, statistical methods and programming in SAS and Stata. Email Stacey Rosenzweig

Susan T. Pastula – Epidemiologist Ms. Pastula, MPH, has 20 years of epidemiology experience including research, project management, data collection, and analysis.  As an Epidemiologist, she coordinated occupational health studies funded jointly by company and unions. She was instrumental in the design, development, and field training of an in-house injury surveillance system for use in manufacturing locations.  She also analyzed employee health claims data related to chronic conditions and healthcare use.  Ms. Pastula has worked in university, industry, and consulting settings and has conducted research in occupational, environmental, pharmacoepidemiology, drug development, and the safety of drugs and medical devices.  She has published in the Journal of Occupational and Environmental Medicine, the International Journal for Quality in Health Care, and the American Journal of Industrial Medicine. Email Sue Pastula

Sarah Irvin – Epidemiologist Ms. Irvin, MS, received her Master’s degree from George Mason University. She holds a B.Sc. in pre-medicine biology from Washington Adventist University. Ms. Irvin spent over five years at Exponent, Inc. in the health sciences consulting area including projects related to epidemiology, toxicology, mechanistic biology, and food and chemical regulatory science.  Ms. Irvin performed research activities on the toxicological properties of dioxin, and maintained an extensive database of literature on dioxin and its mechanisms of action.  She was also the senior research assistant on a large occupational epidemiology study of the mortality of over 20,000 pharmaceutical workers and her work included the collection of primary occupational data, validation of the assembled cohort, vital status ascertainment, working with over 20 states regarding the acquisition of death records, and assisting in the mortality analysis and report creation. Additional projects in which Ms. Irvin was involved included the safety assessment of chemical ingredients in cosmetic products, exclusive use registrations of certain agricultural active ingredients, literature reviews of various compounds for their mechanisms of action and safety in food products, and data abstractions from literature on breast cancer drugs and their health effects. Email Sarah Irvin

Xiaohui Jiang – Biostatistician Ms. Jiang, MS, has more than 10 years of experience as a biostatistician. She has provided data management and analytic expertise on a broad range of projects including evaluations of cancer risk among occupational cohorts, meta-analyses, and the University of Michigan Dioxin Exposure Study.  Ms. Jiang has extensive experience in statistical analysis using many software platforms including SAS, STATA and R Statistical Software. She has co-authored multiple publications in the Journal of Occupational and Environmental Medicine, Chemosphere, and Environmental Science & Technology. Email Xiaohui Jiang